Last updated: October 9, 2026 · Originally published: September 7, 2026 · By Eternal Elixir Editorial
Quick answer: For raising blood NAD+, one 500mg capsule is more than the trials needed: several 12-week studies raised blood NAD+ with 250mg of NMN a day. The largest dose-ranging trial found blood NAD and walking results highest at 600mg and 900mg a day, which one 500mg capsule does not reach. So 500mg is a sensible daily serve inside the studied range, not the top of it. Our pick is Eternal Elixir NMN 500mg: one capsule gives the full 500mg, a bottle holds 90, and it costs $0.67 a day, sent from Sydney within 24 hours.
Still choosing a brand? Our guide to the best NMN supplement in Australia compares the wider market. Eternal Elixir makes NMN 500mg, and it is our pick here, so weigh our view with that in mind. Every competitor price and label detail below was read from that product’s own page in September 2026 and is linked, and the studies are listed in full at the end. We have not lab-tested any of these products.
What NMN 500mg means on an Australian label
NMN is nicotinamide mononucleotide, a building block your cells use to make NAD+, a coenzyme involved in energy metabolism. “NMN 500mg” on a label tells you the amount of NMN in one serve, usually one capsule. It does not tell you how much NAD+ you end up with, and NMN is not the same thing as NAD+. Our NMN vs NAD+ guide explains the difference.
Most Australian NMN capsules now hold 500mg, but not all of them. Bioglan sells a 250mg capsule alongside its 500mg one, and Simply Nootropics uses 250mg capsules with two to a 500mg serve. Melrose FutureLab adds 250mg of dimethylglycine (DMG) to each 500mg capsule. So check two things before you compare prices: the NMN per capsule, and how many capsules make one serve.
Pharmacy labels add limits of their own. Healthy Care and Melrose FutureLab state a maximum of 500mg of NMN a day and a 12-week limit on use, and Bioglan says it is not recommended for more than 12 weeks. Our label says one capsule daily, preferably in the morning. Whichever product you buy, follow its directions.
Is 500mg of NMN enough? What the human trials show
None of the trials below tested 500mg a day for months. What they show is the range around it, and 500mg sits well inside that range. Here is what each dose has been tested for:
| Daily NMN dose | Who and how long | What happened | Study |
|---|---|---|---|
| 250mg | 30 healthy adults, 12 weeks | Whole-blood NAD+ rose significantly, with no obvious adverse effects | Okabe et al., 2022 |
| 250mg | 42 healthy men aged 65 and over, 12 weeks | Blood NAD+ rose. Gains in gait speed and grip strength were only nominally significant, and body composition didn’t change | Igarashi et al., 2022 |
| 250mg | 60 older adults, 12 weeks | The main outcome, a stepping test, did not differ from placebo. Blood NAD+ was higher, 4-metre walking time was shorter and sleep quality scores improved | Morifuji et al., 2024 |
| 250mg | 108 older adults, 12 weeks | All groups, placebo included, improved on sit-to-stand. The afternoon NMN group showed the largest effect on sit-to-stand and drowsiness | Kim et al., 2022 |
| 300mg, 600mg or 900mg | 80 healthy middle-aged adults, 60 days | Blood NAD rose in every NMN group and was highest at 600mg and 900mg. Six-minute walking distance improved more than placebo in all three groups, most at 600mg and 900mg | Yi et al., 2023 |
| 300mg, 600mg or 1,200mg | 48 recreational runners, 6 weeks | Oxygen uptake and power at the ventilatory thresholds rose more than placebo at 600mg and 1,200mg. VO2max did not change | Liao et al., 2021 |
| 1,250mg | 31 healthy adults, up to 4 weeks | A safety study: nothing changed beyond normal variation and there were no severe adverse events | Fukamizu et al., 2022 |
| Single doses of 100mg, 250mg and 500mg | 10 healthy men, a single dose at each level | No significant clinical symptoms, and NMN breakdown products in the blood rose with the dose | Irie et al., 2020 |
A 2026 pooled analysis of 15 randomised trials, 10 of them with safety data, covered doses of 250mg to 2,000mg a day for 14 days to 24 weeks. NMN did not increase adverse events or raise the liver enzymes ALT and AST compared with control. It also found no clear effect on body weight, fasting glucose, HbA1c, blood fats or systolic blood pressure, and a small fall in diastolic pressure (Yang et al., Nutrients, 2026).
Where one 500mg capsule sits: it is double the 250mg a day that raised blood NAD+ in the Okabe, Igarashi and Morifuji trials. It falls between the 300mg and 600mg arms of the Yi trial, and below the 600mg and 900mg arms where blood NAD and walking distance were highest. It is well under the 1,250mg a day that Fukamizu tested for four weeks. So if your goal is simply to raise NAD+, one capsule is enough on the evidence. If you want to match the dose where the Yi trial’s results peaked, 500mg is below it, and nobody has shown that the extra 100mg makes a difference you would notice.
Most of these trials were small, ran for 60 days to 12 weeks, and were funded or co-run by NMN makers. The evidence beyond higher NAD+ levels is modest. Our NMN dosage guide for Australia covers the ranges in more detail, and our article on long-term NMN safety research covers what the trials can and can’t tell you about years of use.
Add NMN 500mg to cart · $59.99
Should you take two capsules?
Not without a reason and a conversation with your doctor. Higher doses have been tested, 900mg a day for 60 days and 1,250mg a day for four weeks, and the pooled analysis found no rise in adverse events up to 2,000mg a day. But our label says one capsule a day, and several pharmacy labels set 500mg as the daily maximum. The trials also show that blood NAD+ rises at 250mg, so one 500mg capsule is already twice the lowest dose that worked.
NMN 500mg cost per serve in Australia
Because most products give 500mg per serve, the real differences are price and pack size. Every row below is converted to the cost of one 500mg serve, using each product’s own label, as of Sep 2026.
| Product | NMN per capsule (label) | Capsules per pack | Serve | Price (AUD, as of Sep 2026) | Cost per 500mg serve | Buy |
|---|---|---|---|---|---|---|
| Eternal Elixir NMN 500mg (our pick) | 500mg | 90 | 1 capsule | $59.99 | $0.67 | Eternal Elixir, ships from Sydney |
| Bulk Nutrients NMN Capsules | 500mg | 120 | 1 to 2 capsules | $79.00 | $0.66 | Bulk Nutrients |
| Naturecan NMN | 500mg | 120 | 1 capsule | $98.00 | $0.82 | Naturecan |
| Healthy Care NMN 500mg | 500mg | 30 | 1 capsule | $32.39 (RRP $64.79) | $1.08 | Chemist Warehouse |
| Bioglan NMN 500 | 500mg | 30 | 1 capsule | $42.49 (RRP $84.99) | $1.42 | Chemist Warehouse |
| Melrose FutureLab NMN 500mg | 500mg, plus 250mg DMG | 30 | 1 capsule | $52.47 (RRP $74.95) | $1.75 | Chemist Warehouse |
| Simply Nootropics Ageless NMN Capsules | 250mg | 30 days at 2 capsules | 2 capsules | $69.00 | $2.30 | Simply Nootropics |
Our price is from our live product page. Other prices were read from the linked pages in September 2026 and change often, especially during pharmacy sales. Melrose FutureLab is $74.95 on its own site.
Add NMN 500mg to cart · $59.99
The spread is wide for the same 500mg: from $0.66 to $2.30 a serve. Over a year of daily use that is roughly $241 at the low end against $840 at the high end. Pack size explains most of it. A 30-capsule pharmacy pack lasts a month, while our 90-capsule bottle lasts three.
Two fair notes. Bulk Nutrients is a cent cheaper than ours per serve on a single bottle, though it adds a flat $9 shipping charge, while we ship free on orders over $100. Naturecan’s 180-capsule pack brings it to $0.79 a serve ($142.00). With multi-bottle pricing ours drops further: five bottles cost $239.96 with the 20% saving, which is $0.53 a serve. Our best NMN supplements in Australia comparison ranks the wider market, and our Melrose FutureLab alternatives and Bioglan NMN review look at two pharmacy brands in detail.
What brand of NMN is best?
The molecule is the same in every brand, so compare what actually differs:
- NMN per capsule. A 500mg capsule gives a full serve in one. A 250mg capsule needs two.
- Capsules per pack. 30 capsules is a month. 90 or 120 is three to four months.
- Cost per 500mg. Divide the price by the number of 500mg serves in the pack.
- What else is in it. DMG, resveratrol or a drink-powder blend can be useful, but you pay for them.
- Testing. Ask the brand for a certificate of analysis for your batch.
On those points our pick is Eternal Elixir NMN 500mg: 500mg in one capsule, 90 capsules per bottle, $0.67 a serve, and a batch certificate on request. If you want the lowest single-pack price per serve, Bulk Nutrients is a cent cheaper. If you want to buy in store today, Healthy Care at Chemist Warehouse is the lowest-cost capsule we found.
The best NMN 500mg at Chemist Warehouse
When we checked in September 2026, the lowest-cost 500mg capsule at Chemist Warehouse was Healthy Care NMN 500mg at $32.39 for 30, or $1.08 a serve. Bioglan NMN 500 was $1.42 a serve, and Melrose FutureLab, which adds DMG, was $1.75. Each is a 30-capsule pack with a 12-week label limit. Chemist Warehouse also sells Microgenics NMN Powder, which works out cheaper per 500mg than any of its capsules, at $0.83. Our guide to buying NMN at Chemist Warehouse covers the full range, and our NMN powder vs capsules comparison explains the trade-offs of a powder.
How to take NMN 500mg
Timing and consistency
Our label says one capsule a day, preferably in the morning, and most people take NMN with breakfast. One 12-week trial of 108 older adults found the afternoon NMN group had the largest effects on sit-to-stand speed and drowsiness, so the evidence on timing is not settled. Pick a time you will keep to. Our guide to taking NMN in the morning or at night goes further.
What people pair it with
Trans-resveratrol is the classic partner. You can buy the two separately as NMN 500mg and Trans-Resveratrol 1200mg, which gives 1,200mg per two-capsule serve, or in one product, Vitasolutions NMN & Resveratrol. We compare the two ingredients in NMN vs resveratrol, and our NMN and resveratrol combinations compared sets the options side by side.
Setting realistic expectations
NMN is not a stimulant. In the Yi trial, blood NAD was already higher at day 30, and walking-test differences showed at days 30 and 60. Many people notice nothing at all, which fits trials that mostly measured blood markers. Our pieces on how long NMN takes to work and NMN before and after cover what to expect.
What works better than NMN?
Nothing has been shown to, because the main alternatives haven’t been tested against NMN head to head. Nicotinamide riboside (NR) also raises blood NAD+ in trials, and our NMN vs NR comparison and Tru Niagen review cover it. AgeMate puts 500mg of NMN in a drink powder with other ingredients, and our look at whether AgeMate’s 500mg NMN serve is enough compares it with capsules. If you are comparing every Australian option, our NMN buyer’s guide for Australia is the place to start.
Who should be careful with NMN
The trials report NMN as well tolerated, but they were short and in generally healthy adults. Talk to your doctor before starting if you are pregnant or breastfeeding, take prescription medicines, or manage an ongoing health condition. NMN products are made for adults, and several Australian labels say not for use in pregnancy or lactation.
Why Eternal Elixir NMN is one 500mg capsule
Eternal Elixir NMN 500mg holds 500mg of nicotinamide mononucleotide in each cellulose capsule, with rice flour as the only other ingredient. The label says one capsule daily, preferably in the morning, and each bottle holds 90.
- A full 500mg in one capsule. No doubling up, as with 250mg capsules.
- Three months per bottle. 90 capsules against 30 in each pharmacy pack we checked.
- $0.67 a serve on one bottle. Two bottles save 10% ($107.98, which also ships free), three save 15% and five save 20%, bringing it to $0.53 a serve.
- Sent from Sydney within 24 hours, with a 30-day money-back guarantee and Afterpay available.
- Batch certificates on request. Our product page says every batch is third-party lab tested for purity and potency, and we will send the current certificate of analysis if you ask.
Who it suits: adults who want a daily 500mg of NMN in one capsule, at one of the lowest costs per serve in Australia, without reordering every month.
Who it doesn’t suit: anyone who wants to buy in store today, anyone who wants a dose in steps smaller than 500mg, and anyone after the absolute lowest single-bottle price, where Bulk Nutrients is a cent cheaper.
NMN 500mg in Australia: frequently asked questions
Is 500mg of NMN enough?
For raising blood NAD+, yes. Trials raised blood NAD+ with 250mg a day over 12 weeks, half of one 500mg capsule. The largest dose-ranging trial found the highest blood NAD and walking results at 600mg and 900mg, so 500mg sits inside the studied range rather than at its top.
Add NMN 500mg to cart · $59.99
What are the benefits of taking 500mg of NMN?
The benefit the trials show most consistently is higher NAD+ in the blood. Some trials also found small improvements in walking tests or sleep quality scores in older adults, but they were small and short. Treat anything beyond higher NAD+ as possible rather than proven.
Can I take 1,000mg of NMN a day?
Doses up to 1,250mg a day have been tested for up to four weeks, and a pooled analysis found no rise in adverse events at up to 2,000mg a day for up to 24 weeks. But our label says one 500mg capsule daily, and some pharmacy labels set 500mg as the maximum. Talk to your doctor before taking more than your label says.
What are the side effects of NMN?
The trials report NMN as well tolerated. The 2026 pooled analysis found no increase in overall or serious adverse events and no rise in liver enzymes compared with control. There is little data on use over years. Speak to your doctor first if you are pregnant or breastfeeding or take prescription medicines.
What brand of NMN is best?
Our pick is Eternal Elixir NMN 500mg: 500mg in one capsule, 90 capsules per bottle, $0.67 a serve, shipped from Sydney. Bulk Nutrients is a cent cheaper per serve on a single bottle, and Healthy Care is the lowest-cost capsule at Chemist Warehouse. Compare the cost per 500mg rather than the pack price.
Add NMN 500mg to cart · $59.99
Which NMN would we choose at Chemist Warehouse?
On cost, Healthy Care NMN 500mg at $1.08 a serve was the lowest-cost capsule when we checked in September 2026, and Microgenics NMN Powder was $0.83 per 500mg. Melrose FutureLab suits people who want DMG in the same capsule. All three carry a 12-week label limit.
Do doctors recommend NMN?
NMN is sold as a supplement, not prescribed as a medicine, and the human trials are small and short. Whether your doctor supports it will depend on your health and any medicines you take, so ask, and bring the label with you.
Should I take NMN 500mg in the morning or at night?
Our label says one capsule daily, preferably in the morning. One trial found slightly larger effects on sit-to-stand speed and drowsiness when older adults took NMN in the afternoon, so timing isn’t settled. Take it at the same time each day.
The verdict: is one NMN 500mg capsule enough?
Our pick: Eternal Elixir NMN 500mg. One capsule gives 500mg of NMN, twice the 250mg a day that raised blood NAD+ in 12-week trials, for $0.67 a day in a 90-capsule bottle, shipped from Sydney within 24 hours.
For most adults, one 500mg capsule a day is a sound, well-studied serve. It won’t match the 600mg or 900mg arms of the largest trial, and nobody has shown that it needs to. Compare products on cost per 500mg, follow your label, and give it at least a month before you judge it.
More reading: our Naturecan review, NAD+ decline by age, or every product in the Eternal Elixir shop.
Sources
- Yi L, Maier AB, Tao R, et al. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. GeroScience. 2023;45(1):29-43. PubMed 36482258
- Okabe K, Yaku K, Uchida Y, et al. Oral administration of nicotinamide mononucleotide is safe and efficiently increases blood nicotinamide adenine dinucleotide levels in healthy subjects. Frontiers in Nutrition. 2022;9:868640. PubMed 35479740
- Igarashi M, Nakagawa-Nagahama Y, Miura M, et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. NPJ Aging. 2022;8(1):5. PubMed 35927255
- Morifuji M, Higashi S, Ebihara S, Nagata M. Ingestion of β-nicotinamide mononucleotide increased blood NAD levels, maintained walking speed, and improved sleep quality in older adults in a double-blind randomized, placebo-controlled study. GeroScience. 2024;46(5):4671-4688. PubMed 38789831
- Kim M, Seol J, Sato T, et al. Effect of 12-week intake of nicotinamide mononucleotide on sleep quality, fatigue, and physical performance in older Japanese adults: a randomized, double-blind placebo-controlled study. Nutrients. 2022;14(4):755. PubMed 35215405
- Liao B, Zhao Y, Wang D, et al. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. Journal of the International Society of Sports Nutrition. 2021;18(1):54. PubMed 34238308
- Fukamizu Y, Uchida Y, Shigekawa A, et al. Safety evaluation of β-nicotinamide mononucleotide oral administration in healthy adult men and women. Scientific Reports. 2022;12(1):14442. PubMed 36002548
- Irie J, Inagaki E, Fujita M, et al. Effect of oral administration of nicotinamide mononucleotide on clinical parameters and nicotinamide metabolite levels in healthy Japanese men. Endocrine Journal. 2020;67(2):153-160. PubMed 31685720
- Yang W, Huang J, Tang Z, Chen C, Sun Y. Safety and metabolism-related outcomes of oral nicotinamide mononucleotide supplementation in adults: a systematic review and meta-analysis. Nutrients. 2026;18(14):2251. PubMed 42514320
- Product pages read in September 2026: Bulk Nutrients NMN Capsules, Naturecan NMN, Simply Nootropics NMN Capsules, Melrose FutureLab NMN Capsules 500mg, and Chemist Warehouse listings for Healthy Care NMN 500mg, Bioglan NMN 500, Melrose FutureLab NMN 500mg and Microgenics NMN Powder (linked in the tables above and in our Chemist Warehouse guide).
- Eternal Elixir NMN 500mg product page and label. eternalelixir.com.au
