Liver & bile support
TUDCA supports liver function and healthy bile flow as part of a daily wellness routine.








A three-bottle metabolic wellness stack featuring TUDCA 500mg, Berberine 500mg, and Reduced L-Glutathione 2000mg for liver, bile, metabolic, and antioxidant support.
TUDCA supports liver function and healthy bile flow as part of a daily wellness routine.
Berberine supports everyday metabolic wellness and nutrition-focused protocols.
Reduced L-Glutathione supports cellular antioxidant defence and normal detoxification processes.
A targeted ingredient used to support liver function, bile flow, and digestive wellness routines.
A plant extract used in wellness routines to support everyday metabolic function and healthy lifestyle protocols.
A reduced-form glutathione supplement designed to support cellular antioxidant defence and normal detoxification processes.
This protocol supports metabolic wellness from three coordinated angles:
Each bottle in this stack has been studied on its own. Here is when those trials measured each change, so you know what to look for and when.
TUDCA is a bile acid that supports liver and bile health, and berberine supports healthy metabolic function. Both work as part of a daily routine, so consistency matters more than any single day.
TUDCA and BerberineIn a 12-week trial, 250mg of glutathione a day reduced wrinkles and improved skin elasticity compared with placebo. This stack provides 2000mg a day.
Reduced L-GlutathioneAt 1000mg a day, natural-killer-cell activity, a measure of immune function, doubled by three months, and glutathione in blood cells rose 30 to 35% by six months.
Reduced L-GlutathioneWhat the full routine supports
TUDCA for liver and bile health.
Berberine for healthy metabolic function.
Reduced glutathione, the antioxidant your cells make themselves.
Measured in the 12-week and three-month glutathione trials.
The TUDCA and berberine trials listed below used higher daily amounts than this stack, so their results are not part of this timeline. Timeframes come from the studies listed below. Everyone responds differently, and changes build with consistent daily use.
Berberine and glutathione go on an empty stomach, TUDCA with a meal. Or follow the directions on each label.
Berberine may interact with blood sugar, blood pressure, anticoagulant, antibiotic, immunosuppressant, and other medicines. Do not use during pregnancy or breastfeeding unless advised by a qualified healthcare professional.
10 published studies on the three ingredients in this stack, the same research listed on each product page. Every link opens the original abstract on PubMed.
1,750 mg of TUDCA daily improved liver and muscle insulin sensitivity by roughly 30% compared with placebo, in a double-blind, randomised trial.
View on PubMed →Reviews how TUDCA acts as a chemical chaperone that reduces endoplasmic-reticulum stress and protects cells, with evidence spanning liver, metabolic, neurological and eye tissues.
View on PubMed →TUDCA reduced endoplasmic-reticulum stress in the liver, normalised blood glucose and restored insulin sensitivity in liver, muscle and fat tissue, establishing the cellular mechanism behind its metabolic effects.
View on PubMed →Oral berberine reduced total cholesterol by 29%, triglycerides by 35% and LDL cholesterol by 25%, working by increasing liver LDL-receptor expression rather than by blocking cholesterol synthesis.
View on PubMed →Berberine 500 mg three times daily reduced waist circumference, systolic blood pressure, triglycerides and post-meal glucose, and improved insulin sensitivity; 36% of participants no longer met the criteria for metabolic syndrome.
View on PubMed →Three months of berberine lowered BMI (31.5 to 27.4 kg/m²), reduced leptin and improved the HOMA-IR insulin-resistance index, while in cell culture it inhibited the formation of new fat cells.
View on PubMed →Across randomised trials, berberine lowered total cholesterol, LDL cholesterol and triglycerides and raised HDL cholesterol compared with control, with no increase in adverse events.
View on PubMed →Daily oral glutathione at 250 or 1,000 mg raised glutathione levels in blood cells, plasma and lymphocytes by 30–35% at the higher dose (260% in cheek cells), lowered the oxidised-to-reduced glutathione ratio, and doubled natural-killer-cell activity after three months.
View on PubMed →250 mg of glutathione daily lowered the melanin index at sun-exposed skin sites, reduced wrinkles and improved skin elasticity compared with placebo.
View on PubMed →500 mg of oral glutathione daily produced a measurable reduction in melanin indices at sun-exposed sites versus placebo and was well tolerated.
View on PubMed →Studies describe each ingredient in the populations shown; results vary between individuals. Links open the original abstracts on PubMed.
You receive all three full-size bottles in one intentional protocol for $126.99 — a saving of $22.98 compared with the $149.97 individual product value.
Or take the full 90-day supply: four bottles for $151.99, a saving of $37.97 on the $189.96 individual product value, with enough of each bottle to last the full 90 days.
Adults who want one daily routine for liver and metabolic support, with an antioxidant alongside it.
TUDCA is a bile acid that supports liver and bile health. Berberine supports healthy metabolic function. Reduced L-glutathione is the antioxidant your cells make themselves, taken here in its reduced form.
Take 2 Reduced L-Glutathione capsules and 1 Berberine capsule first thing in the morning, before food. Take 1 TUDCA capsule with a meal, ideally one with some healthy fat.
No. This is a metabolic wellness support stack, not a treatment or a weight-loss product.
Check with your healthcare professional first. Berberine can interact with some medicines, including those for blood sugar, blood pressure and blood clotting.
TUDCA and Berberine last 90 days at one capsule a day. Reduced L-Glutathione lasts 45 days at two capsules a day, so it is the bottle you reorder first. The 90-day supply evens this out, with enough of each bottle to last the full 90 days.
You get all three full-size bottles in one checkout for $126.99, a saving of $22.98 on the $149.97 they cost separately, and the order ships free.
Yes. The 90-day supply is 1 × TUDCA 500mg, 1 × Berberine 500mg and 2 × Reduced L-Glutathione 2000mg: four full-size bottles, each lasting the full 90 days at the label serve. It is $151.99, a saving of $37.97 on the $189.96 the same bottles cost separately.