Last updated: October 22, 2026 · Originally published: June 2, 2026 · By Eternal Elixir Editorial
Quick Answer
Eternal Elixir NMN 500mg is our pick for the best longevity supplement in Australia. Each capsule holds 500mg of NMN, the label serve is one capsule a day, and a 90-capsule bottle costs $59.99. That is $0.67 a day for a three-month supply, dispatched from Sydney. If you want a second compound, our Spermidine 10mg costs $0.56 a day on the same one-a-day, 90-capsule format.
Eternal Elixir makes three of the nine products compared here, so read this as our pick with the working shown. Competitor prices and labels were read from each seller’s own page in September 2026.
Longevity supplements are capsules and powders taken to support the biology of ageing rather than to fix one symptom. The main groups are the NAD+ precursors NMN and NR, spermidine, the polyphenols resveratrol and pterostilbene, and Ca-AKG. None of them has been shown to extend human lifespan. What you can compare is how much of the active ingredient you get, what a day of it costs, and what the human studies have actually measured.
This guide compares nine longevity supplements sold to Australians: three of our own and six from other brands, including AgeMate, Melrose FutureLab at Chemist Warehouse, Bulk Nutrients, Longevity+ and Naturecan. Every price is in Australian dollars and every cost per day uses the serve printed on that product’s own label. Further down you will find the research on NMN, NR and spermidine, a section for anyone looking for an AgeMate alternative, and answers to the questions Australians search for most.
Table of contents
- 1. Best longevity supplements in Australia compared by daily cost (as of Sep 2026)
- 2. How we ranked these nine longevity supplements
- 3. What counts as a longevity supplement?
- 4. #1 Eternal Elixir NMN 500mg: our pick for most people
- 5. #2 Eternal Elixir Spermidine 10mg: lowest daily cost in this guide
- 6. #3 Eternal Elixir Cellular Longevity Stack: three compounds in one order
- 7. #4 Bulk Nutrients NMN Capsules: lowest price per capsule
- 8. #5 Longevity+ Spermidine 10mg: a larger spermidine tub
- 9. #6 Naturecan Resveratrol Capsules: resveratrol at a lower daily dose
- 10. #7 Melrose FutureLab NMN 500mg: the pharmacy option
- 11. #8 AgeMate Daily Longevity Blend: the best-known NMN drink
- 12. #9 Naturecan Longevity Mix: the most ingredients per scoop
- 13. Our other longevity capsules
- 14. How AgeMate compares with these picks
- 15. What the research on longevity supplements shows
- 16. Vitamins, fish oil and the basics
- 17. Who should check with a doctor first
- 18. The verdict: which longevity supplement suits which buyer
- 19. Longevity supplements: frequently asked questions
- 19.1. What is the best supplement for longevity?
- 19.2. What are the best longevity supplements available in Australia?
- 19.3. Which longevity supplement brands sell in Australia?
- 19.4. Which supplement is best for anti-ageing?
- 19.5. Which tablet is best for longevity?
- 19.6. Do longevity supplements work?
- 19.7. How much do longevity supplements cost per day in Australia?
- 19.8. Can you take NMN and spermidine together?
- 19.9. How long do longevity supplements take to work?
- 20. Sources
- 21. Explore this topic in depth
Best longevity supplements in Australia compared by daily cost (as of Sep 2026)
Cost per day is the single-pack price divided by the number of daily serves in the pack, before postage. Where a label gives a range (one to two capsules), we priced the lower serve and say so.
| # | Product | Type | Price (AUD) | Pack | Daily serve (label) | Cost per day | Buy |
|---|---|---|---|---|---|---|---|
| 1 | Eternal Elixir NMN 500mg | NMN capsule | $59.99 | 90 capsules | 1 capsule (500mg NMN) | $0.67 | Eternal Elixir |
| 2 | Eternal Elixir Spermidine 10mg | Spermidine capsule | $49.99 | 90 capsules | 1 capsule (10mg) with a meal | $0.56 | Eternal Elixir |
| 3 | Eternal Elixir Cellular Longevity Stack | NMN, spermidine and pterostilbene | $139.99 | Three 90-capsule bottles | 1 capsule of each | $1.56 for all three | Eternal Elixir |
| 4 | Bulk Nutrients NMN Capsules | NMN capsule | $79.00 | 120 capsules | 1 to 2 capsules (priced at 1, 500mg NMN) | $0.66 | Bulk Nutrients |
| 5 | Longevity+ Spermidine 10mg | Spermidine capsule | $79.00 | 120 capsules | 1 capsule (10mg) | $0.66 | Longevity+ |
| 6 | Naturecan Resveratrol Capsules | Resveratrol capsule | $61.20 (was $72.00) | 60 capsules | 1 capsule (500mg resveratrol) | $1.02 | Naturecan |
| 7 | Melrose FutureLab NMN 500mg | NMN plus DMG capsule | $52.47 (RRP $74.95) | 30 capsules | 1 capsule (500mg NMN) | $1.75 | Chemist Warehouse |
| 8 | AgeMate Daily Longevity Blend | NMN drink powder | $79 a month on subscription, $99 bought once | 30 scoops | 1 scoop (500mg NMN plus other ingredients) | $2.63 ($3.30 bought once) | AgeMate |
| 9 | Naturecan Longevity Mix | Multi-ingredient drink powder | $88.00 | 150g, 30 scoops | 1 scoop (250mg NMN plus other ingredients) | $2.93 | Naturecan |
Three things decide what a longevity habit really costs once you look past the price on the box.
- Pack size sets how often you reorder. Our bottles hold 90 capsules at one a day, so each lasts three months. The Bulk Nutrients and Longevity+ tubs hold 120. The Melrose FutureLab box holds 30, which means twelve purchases a year.
- Multi-buys change the maths. Our product pages take 10% off two bottles, 15% off three and 20% off five. For NMN that works out at $0.60, $0.57 and $0.53 a day, and every one of those orders clears the $100 free-shipping line. Bulk Nutrients sells four NMN tubs at $67.00 each ($0.56 a day) with a flat $9 postage charge, and Longevity+ takes its spermidine tub to $72.00 on subscription ($0.60 a day).
- Drinks cost more per milligram of NMN. AgeMate gives 500mg of NMN for $2.63 a day on subscription, and Naturecan’s Longevity Mix gives 250mg for $2.93. You are paying for the other ingredients and the powder format, which some people prefer to capsules.
How we ranked these nine longevity supplements
Eternal Elixir makes NMN 500mg, Spermidine 10mg and the Cellular Longevity Stack. They sit first, second and third as our picks, and you should weigh what we say about them with that in mind. We have not changed any competitor’s figures.
The other six are ordered by cost per day at the label serve, lowest first, because that is the number most brands leave you to work out yourself. Beyond price, each entry below covers:
- How much active ingredient is in a daily serve, taken from the label or nutrition panel.
- How long a pack lasts and how the seller ships to Australian addresses.
- What the label tells you not to do, such as a 12-week limit on NMN or a pregnancy warning.
- Testing statements, reported exactly as each seller makes them.
We did not send any product to a laboratory. Every competitor price, count and dose comes from that seller’s own page, read in September 2026. Prices move, especially at Chemist Warehouse, so check the live listing before you buy.
What counts as a longevity supplement?
There is no agreed definition, which is why the category is confusing to shop. In practice the products sold under the longevity label in Australia fall into five groups.
- NAD+ precursors. NMN (nicotinamide mononucleotide) and NR (nicotinamide riboside). The body converts both into NAD+, a coenzyme that cells use in energy metabolism and whose levels fall with age. Our NAD+ supplements guide covers this group in depth, and our NMN versus NR comparison explains the choice between the two.
- Spermidine. A polyamine found in wheat germ, soybeans and aged cheese, studied for its role in autophagy, the cell’s recycling process.
- Polyphenols. Trans-resveratrol and its close relative trans-pterostilbene, studied for their effects on sirtuin signalling and antioxidant defence.
- Ca-AKG. Calcium alpha-ketoglutarate, an intermediate in the cell’s energy cycle.
- Blends and drinks. Powders such as AgeMate and Naturecan’s Longevity Mix that combine a smaller dose of several of the above with vitamins, minerals and amino acids.
Two products both sold as “longevity” can hold entirely different ingredients at very different doses, so compare the label, not the name.
#1 Eternal Elixir NMN 500mg: our pick for most people
Eternal Elixir NMN 500mg gives 500mg of NMN in each capsule, 90 capsules to a bottle, and the label serve is one capsule a day, preferably in the morning. At $59.99 that is $0.67 a day, and one bottle covers a full quarter.
- Dose: 500mg NMN per capsule, one capsule a day.
- Pack: 90 capsules, 90 days.
- Price: $59.99, or $0.60 a day when you buy two bottles at 10% off.
- Dispatch: from Sydney, with free shipping on orders over $100.
Who it suits: anyone who wants a single NAD+ precursor at a full 500mg dose, in one capsule, without reordering every month. It is also the base of most stacks, so it pairs with spermidine or pterostilbene if you add a second compound later.
Who it doesn’t suit: people who want to pick a product up from a pharmacy shelf today, since we sell online only. If you are pregnant or breastfeeding, talk to your doctor first. One more point for accuracy: the best-known 12-week trial used 250mg a day, half of one capsule, so 500mg is above that trial’s dose (other trials have used 300mg to 900mg).
For a closer comparison of NMN products alone, see our best NMN supplements in Australia guide.
Add NMN 500mg to cart · $59.99#2 Eternal Elixir Spermidine 10mg: lowest daily cost in this guide
Eternal Elixir Spermidine 10mg gives 10mg of spermidine per capsule, 90 capsules to a bottle, taken as one capsule a day with a meal. At $49.99 that is $0.56 a day, the lowest daily cost of the nine.
It targets a different process from the NAD+ precursors, so most people add it to NMN rather than swap one for the other. Our guide to taking spermidine and NMN together covers timing, and Ca-AKG versus spermidine sets out how the two autophagy-linked compounds differ.
Who it suits: people already taking an NAD+ precursor who want to cover a second pathway, at a full 10mg in one capsule.
Who it doesn’t suit: anyone who wants strong human trial evidence before spending. The human research on spermidine is thinner than for NMN (see the research section below), and you won’t feel anything from it day to day.
We compare it against other spermidine brands, including powders and wheat-germ extracts, in our best spermidine supplements in Australia guide.
#3 Eternal Elixir Cellular Longevity Stack: three compounds in one order
The Cellular Longevity Stack puts our NMN 500mg, Spermidine 10mg and Trans-Pterostilbene 500mg in one order for $139.99. Bought separately at today’s single-bottle prices, those three bottles cost $174.97, so the stack saves $34.98. At one capsule of each a day, the three bottles last 90 days, which is $1.56 a day for all three.
The stack’s label says to follow the directions on each product and, if you are new to longevity supplements, to start with one product at a time before combining all three. That also makes it easier to tell how each one sits with you.
Who it suits: people who already know they want NMN, spermidine and pterostilbene together and would rather place one order.
Who it doesn’t suit: first-time buyers who aren’t sure they will keep a daily habit, since $139.99 is a bigger first spend than a single bottle. Don’t add separate NMN, spermidine or pterostilbene bottles on top of the stack; it already contains them. If you’d rather build your own combination, our longevity supplement stack guide works through the options by budget.
#4 Bulk Nutrients NMN Capsules: lowest price per capsule
Bulk Nutrients sells 120 capsules of NMN for $79.00, each capsule holding 500mg. The directions say to take one to two capsules daily, with or without food. At one capsule a day that is $0.66, a cent below ours, before a flat $9 postage charge Australia-wide. Buy four tubs and the price drops to $67.00 each.
The product page lists dated lab results for this NMN, the latest from March 2026.
Who it suits: buyers who want the lowest price per 500mg capsule and are happy with a larger tub.
Who it doesn’t suit: anyone ordering a single tub who wants free delivery, since the $9 postage lifts a one-tub order above our single-bottle cost per day.
#5 Longevity+ Spermidine 10mg: a larger spermidine tub
Longevity+ sells 120 capsules of spermidine for $79.00, with 10mg of spermidine trihydrochloride per capsule and a daily dose of one capsule. That is $0.66 a day, or $0.60 on its subscription at $72.00. It also offers 240 capsules for $139.00 and 360 for $189.00. The company’s own comparison table lists New Zealand as the country of manufacture, and its page quotes 5 to 10 working days for delivery, free over $100, with a 90-day money-back guarantee.
Who it suits: spermidine buyers who want four months in one tub.
Who it doesn’t suit: anyone who wants it quickly or wants the lowest daily cost. Our Spermidine 10mg gives the same 10mg for $0.56 a day and ships from Sydney.
#6 Naturecan Resveratrol Capsules: resveratrol at a lower daily dose
Naturecan sells 60 capsules for $61.20 (listed as reduced from $72.00), each with 500mg of resveratrol plus rosemary extract. The page says to take one capsule daily, preferably after a meal. That is $1.02 a day. Naturecan states the product is made in Europe and third-party tested, with a certificate of analysis linked from the page. Shipping starts at $9.99 and is free over $179.
Our Trans-Resveratrol holds 600mg of trans-resveratrol per capsule. The label serve is two capsules a day, with or without food, which gives 1,200mg for $1.33 a day. Naturecan is cheaper per day; ours gives more than twice the daily amount.
Who it suits: people who want a 500mg daily resveratrol dose at a low price.
Who it doesn’t suit: anyone comparing on milligrams per dollar at a higher dose, or who wants a local dispatch. Our best resveratrol supplements guide compares more brands, and pterostilbene versus resveratrol explains the difference between the two.
#7 Melrose FutureLab NMN 500mg: the pharmacy option
Melrose FutureLab NMN 500mg was $52.47 at Chemist Warehouse when we checked, against an RRP of $74.95. The box holds 30 capsules, each with 500mg of NMN and 250mg of dimethylglycine (DMG), taken one a day. That is $1.75 a day on the sale price and $2.50 at the RRP, which is also the price on the brand’s own store.
The label sets a maximum of 500mg of NMN a day and a recommended use of 12 weeks or less, and says not to use it if pregnant or likely to become pregnant, or while breastfeeding. The brand describes the product as Australian made.
Who it suits: buyers who want to collect NMN from a pharmacy today and value the added DMG.
Who it doesn’t suit: anyone planning to take NMN for longer than a few months, given the 30-capsule box and the higher cost per day. Bioglan NMN 500 is the other pharmacy NMN on the Chemist Warehouse site: $42.49 (RRP $84.99) for 30 capsules of 500mg, one a day, and its label says not to use it for more than 12 weeks. Our Melrose FutureLab alternatives comparison goes further.
#8 AgeMate Daily Longevity Blend: the best-known NMN drink
AgeMate sells one product, the Daily Longevity Blend, a powder you mix into water. One level scoop (3.325g) in 240ml of cold water gives 500mg of CellVive NMN alongside glycine, magnesium citrate, MSM, vitamin C, L-theanine and more. A 30-scoop container costs $79 a month on subscription ($2.63 a serve), $149 for two containers a month ($2.48 a serve) or $99 bought once ($3.30 a serve).
The directions say to take it in the morning, daily, for up to 12 weeks. The warnings say adults only, contains phenylalanine and sulfites, and AgeMate’s FAQ recommends against NMN while pregnant or breastfeeding. The page says it is made in Australia and ships from Sydney via AusPost, and the FAQ says AgeMate sells only online, direct to customers.
Who it suits: people who prefer a morning drink to capsules and want the extra ingredients in the same scoop.
Who it doesn’t suit: buyers who mainly want the 500mg of NMN. The same amount in our capsule costs $0.67 a day, about a quarter of the subscription price.
#9 Naturecan Longevity Mix: the most ingredients per scoop
Naturecan’s Longevity Mix is a 150g pouch of lemon or orange powder for $88.00. One 5g scoop in 500ml of water, once a day, gives 250mg of NMN, 250mg of trans-resveratrol, 500mg of Ca-AKG, 5mg of spermidine, 50mg of CoQ10 and 2g of glycine, with vitamin C, magnesium, L-theanine and apigenin. The pouch holds 30 serves, so it costs $2.93 a day. It is suitable for vegans, and Naturecan’s shipping terms are as above.
Who it suits: people who want a small amount of many longevity ingredients in a single drink.
Who it doesn’t suit: anyone who wants a full dose of any one compound. The 250mg of NMN is half of one of our capsules, and the 5mg of spermidine is half of one of our Spermidine 10mg capsules.
Our other longevity capsules
Four more products from our range fit the categories above. Each comes in a 90-capsule bottle and ships from Sydney.
- Pure NR 500mg: 500mg of nicotinamide riboside per capsule, one a day, $59.99 ($0.67 a day). Our NR supplements comparison sets it against other brands.
- Ca-AKG 500mg: 500mg per serve, one capsule a day, $59.99 ($0.67 a day). See our Ca-AKG comparison.
- Trans-Resveratrol: 600mg per capsule, two capsules a day with or without food (1,200mg), 45 serves, $59.99 ($1.33 a day).
- Trans-Pterostilbene 500mg: 500mg per serve, one capsule a day, $64.99 ($0.72 a day). Our pterostilbene guide compares the options.
How AgeMate compares with these picks
AgeMate no longer sells a standalone NMN capsule; its store lists the Daily Longevity Blend and its welcome kits. You can’t buy it in a pharmacy either, because AgeMate sells online only. So an AgeMate equivalent depends on what you want from it.
- If you want the 500mg of NMN: our NMN 500mg gives the same amount in one capsule for $0.67 a day, against $2.63 on AgeMate’s subscription.
- If you want the drink and the extra ingredients: Naturecan’s Longevity Mix is the nearest match on format, though it has 250mg of NMN rather than 500mg.
- If you want NMN plus a second compound: our Cellular Longevity Stack adds spermidine and pterostilbene for $1.56 a day.
Our AgeMate alternatives guide compares more options. If you are weighing other subscription brands, see our TMRW alternatives and DoNotAge alternatives guides.
What the research on longevity supplements shows
Marketing in this category runs well ahead of the evidence, so here is what has actually been measured in people, and what hasn’t.
NMN
Kim and colleagues (Nutrients, 2022) ran a randomised, double-blind, placebo-controlled trial in 108 older Japanese adults who took 250mg of NMN or a placebo once a day for 12 weeks, in the morning or the afternoon. The afternoon NMN group showed the largest improvements in a sit-to-stand test of leg function and in drowsiness scores.
Yi and colleagues (GeroScience, 2023) gave 80 healthy middle-aged adults a placebo or 300mg, 600mg or 900mg of NMN once a day for 60 days. Blood NAD+ rose in every NMN group, most at 600mg and 900mg, six-minute walking distance improved against placebo, and no safety problems were found. The lead author works for an NMN supplier, which is worth knowing when you read it.
NR
Martens and colleagues (Nature Communications, 2018) ran a crossover trial of two six-week periods in healthy middle-aged and older adults. NR was well tolerated and raised NAD+ metabolism. The authors described the effects on physical function as “initial insight” and called for further trials.
Spermidine
The most cited spermidine paper, Eisenberg and colleagues (Nature Medicine, 2016), found that spermidine in the diet extended lifespan in mice and supported heart function in old mice and in rats. The human part was observational only: people whose food questionnaires showed more dietary spermidine had lower blood pressure. That is an association, not a supplement trial.
The strongest human trial points the other way. In the SmartAge trial (Schwarz and colleagues, JAMA Network Open, 2022), 100 adults aged 60 to 90 took a wheat-germ extract giving 0.9mg of spermidine a day, or a placebo, for 12 months. Memory performance did not change compared with placebo. That dose is far below a 10mg capsule, so the trial doesn’t tell us what 10mg does in people. We know of no published trial that has shown a benefit at 10mg either.
What hasn’t been shown
- No supplement sold in Australia has been shown to extend human lifespan.
- The NMN trials ran for 60 days to 12 weeks. There are no long-term human outcome data.
- Animal lifespan results for spermidine, NMN and resveratrol do not carry over to people automatically.
If you choose to start with the most studied group, an NAD+ precursor is the place to begin.
Add NMN 500mg to cart · $59.99Vitamins, fish oil and the basics
People searching for the best vitamins for longevity usually want to know whether a multivitamin or fish oil belongs in the same routine. No vitamin has been shown to extend lifespan either. If your diet is short of a nutrient, fixing that comes before any longevity compound, and a blood test with your GP is the way to find out. Healthdirect’s vitamins and minerals page explains who may need a supplement.
We don’t sell multivitamins, vitamin D, fish oil, CoQ10 or creatine, so buy those from a pharmacy or supermarket. Our range sticks to NAD+ precursors, spermidine, polyphenols and Ca-AKG. For a broader view of the local market, see our guides to the top Australian supplement brands and the best anti-ageing supplements, and our Everlab review if you are considering biomarker testing first.
Who should check with a doctor first
- Anyone taking prescription medicine. AgeMate’s own FAQ notes that NMN may interact with medications in ways that aren’t yet known.
- Anyone pregnant, trying to conceive or breastfeeding. The Melrose FutureLab and Bioglan labels and AgeMate’s FAQ advise against NMN in pregnancy or while breastfeeding.
- Anyone under 18. Several labels here, including AgeMate’s and Bioglan’s, say adults only.
- Anyone preparing for surgery or managing a health condition, as our stack’s safety note says.
The verdict: which longevity supplement suits which buyer
- For most people: Eternal Elixir NMN 500mg, at $0.67 a day for a full 500mg dose in a three-month bottle.
- For the lowest daily cost: Eternal Elixir Spermidine 10mg at $0.56 a day, ideally alongside an NAD+ precursor.
- For three compounds in one order: the Cellular Longevity Stack at $1.56 a day for NMN, spermidine and pterostilbene.
- For the cheapest NMN capsule on a big tub: Bulk Nutrients, at $0.66 a day before postage.
- For a pharmacy purchase today: Melrose FutureLab NMN from Chemist Warehouse, at $1.75 a day on sale.
- For a morning drink: AgeMate at $2.63 a day on subscription, or Naturecan’s Longevity Mix at $2.93.
Longevity supplements: frequently asked questions
What is the best supplement for longevity?
Our pick is Eternal Elixir NMN 500mg. NAD+ precursors such as NMN have the most human trial data of the longevity compounds, and our capsule gives a full 500mg in one capsule a day for $0.67, in a 90-capsule bottle. Eternal Elixir makes it, so weigh our view with that in mind.
Add NMN 500mg to cart · $59.99
What are the best longevity supplements available in Australia?
The nine compared here are Eternal Elixir NMN 500mg, Eternal Elixir Spermidine 10mg, the Eternal Elixir Cellular Longevity Stack, Bulk Nutrients NMN Capsules, Longevity+ Spermidine 10mg, Naturecan Resveratrol, Melrose FutureLab NMN 500mg, AgeMate Daily Longevity Blend and Naturecan Longevity Mix. They range from $0.56 to $2.93 a day at each product’s standard price.
Which longevity supplement brands sell in Australia?
The longevity supplement brands in this comparison reach Australian buyers in different ways. Eternal Elixir sells online and dispatches from Sydney. Bulk Nutrients sells online with a flat $9 postage charge. Longevity+ lists New Zealand as its country of manufacture and quotes 5 to 10 working days for delivery. Naturecan states its resveratrol is made in Europe. Melrose FutureLab and Bioglan NMN are the two pharmacy options on the Chemist Warehouse site. AgeMate says it is made in Australia and sells only online, direct to customers. Our pick across these brands is Eternal Elixir NMN 500mg, and we make it.
Which supplement is best for anti-ageing?
No supplement has been shown to slow ageing in people. If you want to start with the most studied group, choose an NAD+ precursor such as NMN or NR. Our pick is Eternal Elixir NMN 500mg at $0.67 a day.
Which tablet is best for longevity?
Most longevity products are capsules rather than tablets. The one we recommend first is Eternal Elixir NMN 500mg, one capsule a day. If you prefer a drink, AgeMate and Naturecan sell powders instead, at a higher cost per day.
Do longevity supplements work?
It depends on what you mean by work. Trials show NMN raises blood NAD+ and has improved some measures of physical function and fatigue over 60 days to 12 weeks. No trial has shown that any longevity supplement extends human lifespan, and a 12-month spermidine trial found no change in memory.
How much do longevity supplements cost per day in Australia?
In this comparison, from $0.56 a day for Eternal Elixir Spermidine 10mg to $2.93 a day for Naturecan’s Longevity Mix, at each product’s standard price. AgeMate bought once without a subscription works out at $3.30 a day.
Can you take NMN and spermidine together?
Yes, they are commonly combined because they target different processes: NAD+ metabolism and autophagy. Our stack’s label suggests starting one product at a time before combining them. Talk to your doctor or pharmacist first if you take prescription medicine.
How long do longevity supplements take to work?
The NMN trials measured changes after 60 days to 12 weeks of daily use. Longevity compounds are not stimulants, so don’t expect to feel a difference within days.
Sources
- Kim M, Seol J, Sato T, et al. Effect of 12-week intake of nicotinamide mononucleotide on sleep quality, fatigue, and physical performance in older Japanese adults: a randomized, double-blind placebo-controlled study. Nutrients. 2022;14(4):755. PubMed
- Yi L, Maier AB, Tao R, et al. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. GeroScience. 2023;45(1):29-43. PubMed
- Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nature Communications. 2018;9(1):1286. PubMed
- Eisenberg T, Abdellatif M, Schroeder S, et al. Cardioprotection and lifespan extension by the natural polyamine spermidine. Nature Medicine. 2016;22(12):1428-1438. PubMed
- Schwarz C, Benson GS, Horn N, et al. Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline: a randomized clinical trial. JAMA Network Open. 2022;5(5):e2213875. PubMed
- Product labels and prices: each seller’s product page, linked in the comparison table, read in September 2026.
More longevity guides
Best NMN supplements in Australia
Best spermidine supplements in Australia
Building a longevity supplement stack
All supplement guides
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