In 80 adults, 1 g a day for 21 days improved sleep quality, with more deep and REM sleep and better energy, mood and alertness the next day, versus placebo.
Read the abstract →





Common forms such as oxide, citrate and glycinate raise magnesium in the blood, but research has not shown them raising it in the brain. Magnesium L-threonate binds magnesium to L-threonate, a metabolite of vitamin C that is actively transported across the blood-brain barrier.
Inside the brain, magnesium is a natural gatekeeper of the NMDA receptor, the switch behind learning and memory. In the 2010 Neuron study, raising brain magnesium with L-threonate increased synapse density and improved learning and memory.
Each 2,000 mg serve matches the top of the daily dose range used in the 12-week clinical trial, in three vegetable capsules.
Most forms are made for everyday top-ups or digestion. L-threonate is the form shown to raise magnesium in the brain, and the one tested in human trials for memory and sleep. Swipe the table to compare.
| Property | Eternal ElixirL-Threonate | Oxide | Citrate | Glycinate |
|---|---|---|---|---|
| What it's made for | Brain magnesium: memory, focus and sleep | Cheap, high dose, often for constipation | Everyday magnesium | Everyday magnesium, gentle form |
| Reaches the brain | Raised brain magnesium Where other forms did not · Neuron, 2010 (lab study) | Not shown | Not shown | Not shown |
| Memory and focus | Better working memory and executive function 2016 and 2022 trials vs placebo | Not the focus | Not the focus | Not the focus |
| Sleep | More deep and REM sleep Plus next-day energy and focus · 2024 trial, 80 adults vs placebo | Not the focus | Not the focus | Popular for sleep, few trials |
Sleep tends to shift first. Focus and recall build over the weeks after.
Three capsules a day with a meal.
Easier to switch off, and you wake more refreshed.
More deep and REM sleep, and better next-day energy and mood in a 2024 trial.
Overall cognitive ability improved at 6 and 12 weeks in a 12-week trial.
One serve is 2 g, in line with the 1 to 2 g a day used in the human trials. Here is the clearest result, then three more.
The adults in this trial had mild memory and concentration complaints. They took 1.5 to 2 g of magnesium L-threonate a day, and overall cognitive ability improved, most clearly in working memory and executive function.
Liu G et al. Journal of Alzheimer's Disease, 2016. Read the abstract →
Years younger in "brain age" after 12 weeks
In 80 adults, 1 g a day for 21 days improved sleep quality, with more deep and REM sleep and better energy, mood and alertness the next day, versus placebo.
Read the abstract →In healthy adults, 30 days of magnesium L-threonate improved memory scores versus placebo.
Read the abstract →In rats, L-threonate raised magnesium in the brain where other forms did not, and that went with better learning and memory.
Read the abstract →Magnesium L-threonate is magnesium bound to L-threonate, a compound your body makes when it breaks down vitamin C. Each serve is 2,000 mg in three vegetable capsules, with a little rice flour and nothing else.
The ingredientPlate I
Magnesium L‑Threonate
Magnesium bound to L-threonate · a vitamin C metabolite
Magnesium L-threonate · C8H14MgO10 · one magnesium ion, two threonate ions
Good to know. For adults. Check with your healthcare professional first if you're pregnant or breastfeeding, have a kidney condition or take medication.
The serve is always three capsules with a meal. What changes is when you take them.
Magnesium L-threonate makes a natural evening anchor. It pairs with NMN for cellular energy, and with ginseng or methylene blue for daytime focus.


Day and night: NMN tops up NAD+ for daytime energy, while magnesium L-threonate anchors your evening wind-down.


A natural rhythm: ginseng for daytime vitality, magnesium L-threonate to switch off and rest at night.


Focus by day, rest by night: methylene blue for daytime clarity, magnesium L-threonate for the evening.


Two pillars of a longevity routine: spermidine supports cellular renewal while magnesium L-threonate supports restful sleep.
Energy. Mood. Deep sleep.






A day-and-night routine for the mind: ginseng for daytime energy and focus, affron® saffron for a positive mood, and magnesium L-threonate for a calm mind and deep sleep.
Magnesium L-Threonate is already in the stack, so you won't need a separate bottle.
Three capsules a day of the magnesium form made to reach the brain. Stock up and save up to 20%.
3 bottles · $1.70 a day
Free shipping over $100, fast Australian dispatch · Afterpay available

Review Magnesium L-Threonate 2000mg | Brain & Sleep Support