Best Anti-Aging Supplements in Australia 2026: 8 Science-Backed Products Compared

Last updated: September 26, 2026 · Originally published: May 5, 2026 · By Eternal Elixir Editorial

Anti-ageing supplements sold in Australia fall into two groups. Cellular products (NMN, resveratrol, spermidine and Ca-AKG) aim at energy metabolism and cell maintenance. Skin products (mostly collagen) aim at how skin looks and feels. This guide compares eight anti aging supplements in Australia on AUD price, dose per serve, cost per day and the human evidence behind each, and it says plainly where that evidence is thin. No supplement here has been shown to extend human lifespan.

Eternal Elixir makes four of the eight products below: NMN 500mg, Trans-Resveratrol, Spermidine 10mg and Ca-AKG 500mg. They are our picks and they sit at the top of the list, so weigh that when you read it. Every competitor figure comes from the seller’s own product page, read in September 2026.

Comparison Table: 8 Anti-Aging Supplements in Australia

Prices in AUD as of Sep 2026. Cost per day is the pack price divided by the number of label serves.

Two notes on the table. Bulk Nutrients is one cent a day cheaper than our NMN at the same 500mg dose, and we say so in its entry. Vida Glow showed a 20% off sitewide banner when we checked, so its checkout price may be lower than the listed $70.00.

#1. Eternal Elixir NMN 500mg: Best Overall NAD+ Precursor

Label facts: 500mg of NMN (nicotinamide mononucleotide) per capsule, one capsule a day, preferably in the morning. 90 capsules to a bottle, so one bottle lasts 90 days. $59.99, or $0.67 a day.

NAD+ is a coenzyme your cells use to turn food into energy, and blood levels fall with age. NMN is a direct building block for it, which is why NMN leads most longevity stacks. Of the cellular supplements on this list, it also has the most human trial data:

• Yi et al., GeroScience, 2023. 80 healthy adults aged 40 to 65 took placebo or 300mg, 600mg or 900mg of NMN a day for 60 days in a randomised, double-blind trial. Blood NAD rose in every NMN group, and six-minute walking distance improved more than with placebo. Both results were highest at 600mg and 900mg, and no safety issues were found. Three authors worked for Abinopharm or ABA Chemicals.
• Igarashi et al., npj Aging, 2022. 42 healthy men aged 65 and over took 250mg a day or placebo for 12 weeks. Blood NAD rose, and gait speed and grip strength showed nominal improvements that the authors said need larger studies.

Our dose against the trials: 500mg sits between the 300mg and 600mg arms of the Yi trial and above the 250mg in the older-men trial. It is a little below the 600mg arm where results peaked. Australian pharmacy NMN labels we checked set 500mg a day as the maximum and 12 weeks or less as the use period, and the human trials above ran no longer than 12 weeks. Our NMN dosage guide covers timing and duration.

Who it suits: anyone starting a first longevity supplement who wants one capsule and one clear dose. Who it doesn’t: people who want an all-in-one drink, and anyone under 18, pregnant or breastfeeding. If you take prescription medicines, talk to your doctor first. For more NMN options, see our roundup of the best NMN supplements in Australia and how NMN compares with NR.

#2. Eternal Elixir Trans-Resveratrol: Best Resveratrol to Pair With NMN

Label facts: 600mg of trans-resveratrol per capsule from Polygonum cuspidatum (Japanese knotweed), listed at 98% purity on the product page. The label serve is two capsules (1,200mg) a day, with or without food. 90 capsules make 45 serves, $59.99, or $1.33 a day.

Resveratrol is a plant polyphenol found in grape skins and knotweed. It is the supplement most often paired with NMN. The human trials in healthy people used far smaller doses than our serve:

• Evans et al., Nutrients, 2017. 80 postmenopausal women aged 45 to 85 took 75mg of trans-resveratrol twice a day (150mg a day) or placebo for 14 weeks. Blood-flow responsiveness in the brain rose 17% against placebo, and verbal memory and overall cognitive scores improved. The resveratrol was supplied by DSM, its manufacturer.
• Witte et al., Journal of Neuroscience, 2014. 46 healthy, overweight older adults took 200mg a day or placebo for 26 weeks (23 per group). The resveratrol group retained more words over 30 minutes.

Our dose against the trials: our 1,200mg serve is eight times the 150mg in the Evans trial and six times the 200mg in the Witte trial. No trial has shown that a higher dose works better, so the higher dose is not a proven advantage. What it does mean is that one bottle covers well above trial amounts for 45 days. Our resveratrol dosage guide goes through the trial doses in detail.

Who it suits: people already taking NMN who want to add resveratrol. Who it doesn’t: anyone on warfarin or other medicines that resveratrol labels warn about, unless their doctor agrees, and anyone pregnant or breastfeeding. See our best resveratrol supplements in Australia for the wider field.

#3. Eternal Elixir Spermidine 10mg: Best for a Higher-Dose Spermidine Trial

Label facts: 10mg of spermidine (as spermidine trihydrochloride) per capsule, one capsule a day with a meal. 90 capsules to a bottle, $49.99, or $0.56 a day.

Spermidine is a polyamine found in wheat germ, soybeans, mushrooms and aged cheese. In lab and animal studies it switches on autophagy, the process cells use to break down and recycle worn-out parts. Human evidence is much thinner, and the largest trial was negative on its main outcome:

• Schwarz et al., JAMA Network Open, 2022 (the SmartAge trial). 100 adults aged 60 to 90 who reported memory concerns took a wheat-germ extract giving 0.9mg of spermidine a day, or placebo, for 12 months. Memory performance did not change against placebo. Exploratory analyses hinted at effects on verbal memory and inflammation, which the authors said need testing at higher doses. Several authors reported equity interests in, or advisory roles for, The Longevity Labs.

Our dose against the trial: our 10mg capsule is about eleven times the 0.9mg in SmartAge. That is the point of this product: the trial authors themselves called for higher doses. But no published trial has yet tested 10mg a day for any outcome, so what that dose does in people is not known. Our spermidine dosage guide and our roundup of the best spermidine supplements in Australia go into the detail.

Who it suits: people who want to add spermidine at a dose well above what food provides, and who accept that the evidence is early. Who it doesn’t: anyone wanting a proven effect, and anyone pregnant, breastfeeding or under 18.

#4. Eternal Elixir Ca-AKG 500mg: Best Value AKG Supplement

Label facts: 500mg of calcium alpha ketoglutarate per capsule, one capsule a day. 90 capsules to a bottle, $59.99, or $0.67 a day.

Alpha-ketoglutarate is a normal product of the body’s energy cycle, and Ca-AKG is the calcium salt used in supplements. The human evidence is one uncontrolled study:

• Demidenko et al., Aging, 2021. A retrospective analysis of 42 people who took Rejuvant, a formula with 1,000mg of Ca-AKG plus vitamin A or vitamin D, for an average of 7 months. Their DNA methylation age, a lab estimate of biological age, averaged 8 years lower at the end. There was no placebo group, the authors said placebo-controlled testing is needed, and one author is a consultant and board member for the company that sells Rejuvant.

A 2020 study in mice (Asadi Shahmirzadi et al., Cell Metabolism) found Ca-AKG from middle age reduced frailty. That is an animal result and does not tell you what Ca-AKG does in people.

Our dose against the study: our 500mg capsule is half the 1,000mg in the Rejuvant formula, and it contains no added vitamins. For how it compares with NMN as a first pick, see Ca-AKG vs NMN, and for other brands see our best Ca-AKG supplements in Australia.

Who it suits: people who track their biological age with lab tests and want an affordable product with one ingredient. Who it doesn’t: anyone expecting to feel a difference, or wanting placebo-controlled human evidence first.

#5. Bulk Nutrients NMN Capsules: Lowest Price per 500mg of NMN

Label facts: 500mg of β-NMN per capsule, 120 capsules, $79.00 ($0.66 a day at one capsule). Directions are one to two capsules a day with or without food. The product is labelled a formulated supplementary sports food and is not for children under 15. The page showed 4.64 stars from 137 reviews.

Bulk Nutrients is an Australian-owned brand that blends, packs and ships from its factory in southern Tasmania. Its NMN capsule matches ours at 500mg and is one cent a day cheaper, with 30 more capsules in the bottle. It is the pick if the lowest price per 500mg is what matters most to you. Our NMN ranks above it because it is our product, and because we pair it with the other single ingredients in this list for people building a stack. Our Bulk Nutrients review covers the brand in full.

Who it suits: price-first NMN buyers and existing Bulk Nutrients customers. Who it doesn’t: anyone who wants the same brand across NMN, resveratrol, spermidine and Ca-AKG.

#6. Herbs of Gold Resveratrol AdvantAGE: Best Resveratrol With Vitamin C and Zinc

Label facts: each capsule has Japanese knotweed root extract standardised to 250mg of resveratrol, plus 50mg of vitamin C, 50mg of lysine, 25mg each of glycine and proline, rutin and 5mg of zinc. One capsule a day with food, for adults and children over 12. 60 capsules, $78.50, or $1.31 a day.

Herbs of Gold is an Australian brand. This formula gives a moderate resveratrol dose, above the 150mg a day used in the Evans trial, alongside vitamin C, zinc and amino acids. Its daily cost is close to ours, but our serve gives 1,200mg of trans-resveratrol against its 250mg of resveratrol.

Who it suits: people who want resveratrol with vitamin C and zinc in one capsule. Who it doesn’t: anyone who wants a single-ingredient resveratrol, or who already takes zinc.

#7. AgeMate Daily Longevity Blend: Best All-in-One Scoop

Label facts: one 3.325g scoop gives 500mg of CellVive NMN plus 14 other actives, including 1.1g of glycine, 300mg of magnesium citrate (about 46mg of magnesium), 300mg of MSM, 250mg of vitamin C and 200mg of L-theanine. $79 a month on the single subscription (30 scoops, $2.63 a day), $149 for the double subscription (60 scoops) or $99 to buy once. Directions say daily for up to 12 weeks. Adults only, contains phenylalanine and sulfites, and not recommended in pregnancy or breastfeeding.

AgeMate is made in Australia and ships from Sydney. Its NMN dose matches ours, and its L-theanine matches the 200mg used in a trial of that ingredient. The rest of the scoop is a light vitamin and mineral layer. The trade-off is price: for the NMN alone you pay about four times what our capsule costs. Our guide to what is in the AgeMate scoop reads the label line by line, and our AgeMate alternatives comparison covers the options.

Who it suits: people who take no other supplements and want one flavoured drink. Who it doesn’t: anyone mainly after the NMN, or already taking a multivitamin or magnesium.

#8. Vida Glow Natural Marine Collagen: Best for Skin

Label facts: 3,000mg of hydrolysed marine collagen per 3g sachet, 30 sachets, $70.00 listed ($2.33 a day at one sachet). The directions allow one to three sachets a day. The collagen comes from fish farmed in Europe, so it is not for vegetarians or people with a fish allergy.

Collagen is the one ingredient in this list aimed at skin rather than cells, and it has the best skin evidence of any supplement here. A meta-analysis by de Miranda et al. (International Journal of Dermatology, 2021) pooled 19 randomised, double-blind trials with 1,125 participants aged 20 to 70, 95% of them women. Hydrolysed collagen improved skin hydration, elasticity and wrinkles against placebo, typically over about 90 days. The trials used different products and doses, so the result applies to collagen peptides in general rather than to one brand.

We do not sell collagen, and we include it because skin is what many people mean by anti-ageing. For more skin options, see our best skin supplements in Australia.

Who it suits: people whose main goal is how their skin looks and feels. Who it doesn’t: vegetarians, vegans and anyone with a fish allergy.

How We Evaluated These Anti-Aging Supplements

We are a supplement brand, not an independent reviewer, and our own products sit at #1 to #4. Within that, here is what we looked at for every product:

• Label clarity: a stated amount of the active per capsule, scoop or sachet, and a clear serve size.
• Human evidence: randomised trials in people, with the dose, length and result, and a plain note when the evidence is animal-only, uncontrolled or negative.
• Dose against the trials: whether the label serve is below, at or above what the trials used.
• Price in AUD: the pack price from the seller’s own page in September 2026, divided by the number of label serves.
• Availability in Australia: whether you can buy it from an Australian store or brand site.

We did not lab-test any product ourselves, and we do not use testimonials or ratings we cannot see on a live page. We replaced products from the older version of this guide that we could not find on sale or could not verify.

How to Build an Anti-Aging Stack: Beginner to Advanced

The simplest rule is one new product at a time, for at least eight to twelve weeks, so you can tell what each one does for you. Here is how the pieces fit together:

Starting out: NMN on its own

One 500mg capsule of NMN each morning is the easiest start and the option with the most human data. Give it a full course before adding anything.

Adding a second: resveratrol or spermidine

If you want to add a second ingredient, trans-resveratrol is the common partner for NMN, and spermidine is the other popular choice. Pick one, not both at once. If you want NMN and spermidine together, our Cellular Longevity Stack bundles NMN, spermidine and trans-pterostilbene, so do not buy it on top of a separate NMN bottle.

Advanced: Ca-AKG and a skin layer

Ca-AKG suits people who track biological-age tests and want to see whether their number moves. If skin is your priority, collagen is the ingredient with the best skin evidence, and it works independently of the cellular stack.

For fully costed stacks at several budgets, see our best longevity supplement stack in Australia and our guide to building a complete longevity stack. If you are choosing by age and sex, our guides to the best supplements for women over 40 and men over 40 narrow the list. Our roundup of the best NAD+ supplements in Australia covers NMN, NR and NAD+ products side by side.

Safety: Who Should Be Careful

Short-term trials of the ingredients above reported them as well tolerated, but a few cautions apply across the list:

• Pregnancy, breastfeeding and under-18s: the NMN and blend labels we checked are for adults only and advise against use in pregnancy or breastfeeding. The same caution is sensible for the other cellular ingredients.
• Medicines: resveratrol labels warn it may affect how some medicines work, including warfarin. If you take any prescription medicine, talk to your doctor before starting.
• Duration: NMN trials ran up to 12 weeks, and pharmacy NMN labels say 12 weeks or less. Check with your doctor before taking it for longer.
• Allergies: marine collagen comes from fish.

No supplement replaces the basics that the ageing research keeps returning to: regular exercise, enough sleep, not smoking and a varied diet.

Frequently Asked Questions

What is the best anti-aging supplement in Australia?

Our pick is Eternal Elixir NMN 500mg, which we make. It gives 500mg of NMN in one capsule a day, 90 capsules to a bottle, for $0.67 a day, and NMN has the most human trial data of the cellular options. Bulk Nutrients NMN is one cent a day cheaper at the same dose. If skin is your goal rather than cellular health, hydrolysed collagen has the stronger evidence.

Add NMN 500mg to cart · $59.99

Is there one supplement that does the most for anti-aging?

No supplement has been proven to slow human ageing, so no single product stands above the rest. For cellular health, NMN is our first choice because it has randomised human trials showing it raises blood NAD. For visible skin changes, collagen peptides have the most trial data, with a meta-analysis of 19 trials showing better skin hydration, elasticity and wrinkles against placebo.

What are the best supplements for ageing?

For healthy ageing, the four with the most attention are NMN, resveratrol, spermidine and Ca-AKG, in roughly that order of human evidence. NMN has several randomised trials. Resveratrol has small trials at much lower doses than most supplements. Spermidine’s largest trial was negative on its main outcome. Ca-AKG has one uncontrolled study. Collagen is the separate choice for skin.

What supplements make your face look younger?

Hydrolysed collagen is the supplement with the best evidence for skin. In the de Miranda meta-analysis, 19 randomised trials found improved skin hydration, elasticity and wrinkles against placebo, usually after about 90 days. Results depend on the product and dose, and sun protection and not smoking also matter a great deal for how skin ages. We do not sell collagen. Our skin supplements guide compares the options.

Are longevity supplements worth it?

They are worth it if you go in with realistic expectations. The best of them change blood markers in short trials, and none has been shown to extend human life. If you want to try one, choose a single ingredient with a clear dose, give it a full course and judge it on how you feel and on any tests you track.

Start with NMN 500mg · $59.99

How long do anti-ageing supplements take to work?

In the NMN trials, blood NAD was higher by day 30. The resveratrol trials ran 14 to 26 weeks, and the collagen trials usually about 90 days. Many people notice nothing obvious, because the changes measured are in blood markers and tests rather than feelings.

Can you take NMN, resveratrol and spermidine together?

Many people do, and the three work on different processes. No trial has tested the three together, so add them one at a time. If you take any medicines, especially warfarin, check with your doctor before adding resveratrol.

Do anti-ageing supplements extend lifespan?

Not in people, as far as anyone has shown. Lifespan gains for Ca-AKG and spermidine come from mice and other animals. Human trials measure shorter-term markers such as blood NAD, memory scores or biological-age estimates.

Final Rankings Recap

1. Eternal Elixir NMN 500mg: best overall NAD+ precursor, $0.67 a day.
2. Eternal Elixir Trans-Resveratrol: best resveratrol to pair with NMN, $1.33 a day.
3. Eternal Elixir Spermidine 10mg: best for a higher-dose spermidine trial, $0.56 a day.
4. Eternal Elixir Ca-AKG 500mg: best value AKG supplement, $0.67 a day.
5. Bulk Nutrients NMN Capsules: lowest price per 500mg of NMN, $0.66 a day.
6. Herbs of Gold Resveratrol AdvantAGE: best resveratrol with vitamin C and zinc, $1.31 a day.
7. AgeMate Daily Longevity Blend: best all-in-one scoop, $2.63 a day.
8. Vida Glow Natural Marine Collagen: best for skin, $2.33 a day.

Verdict: Which Anti-Aging Supplement Should You Buy?

If you want one anti-ageing supplement for cellular health, start with NMN. Eternal Elixir NMN 500mg gives the full 500mg label dose in one capsule for $0.67 a day, 90 capsules to a bottle, shipped from Sydney. Add trans-resveratrol or spermidine later if you want to build a stack, and choose collagen if your goal is skin. Whatever you pick, give it a full course and keep your expectations tied to what the trials actually showed. You can browse the full range in our shop.

Sources

• Yi L, Maier AB, Tao R, et al. The efficacy and safety of β-nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: a randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial. GeroScience. 2023;45(1):29-43. PubMed 36482258
• Igarashi M, Nakagawa-Nagahama Y, Miura M, et al. Chronic nicotinamide mononucleotide supplementation elevates blood nicotinamide adenine dinucleotide levels and alters muscle function in healthy older men. npj Aging. 2022;8(1):5. PubMed 35927255
• Evans HM, Howe PR, Wong RH. Effects of resveratrol on cognitive performance, mood and cerebrovascular function in post-menopausal women; a 14-week randomised placebo-controlled intervention trial. Nutrients. 2017;9(1):27. PubMed 28054939
• Witte AV, Kerti L, Margulies DS, Flöel A. Effects of resveratrol on memory performance, hippocampal functional connectivity, and glucose metabolism in healthy older adults. Journal of Neuroscience. 2014;34(23):7862-7870. PubMed 24899709
• Schwarz C, Benson GS, Horn N, et al. Effects of spermidine supplementation on cognition and biomarkers in older adults with subjective cognitive decline: a randomized clinical trial. JAMA Network Open. 2022;5(5):e2213875. PubMed 35616942
• Demidenko O, Barardo D, Budovskii V, et al. Rejuvant, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test. Aging. 2021;13(22):24485-24499. PubMed 34847066
• Asadi Shahmirzadi A, Edgar D, Liao CY, et al. Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice. Cell Metabolism. 2020;32(3):447-456. PubMed 32877690
• de Miranda RB, Weimer P, Rossi RC. Effects of hydrolyzed collagen supplementation on skin aging: a systematic review and meta-analysis. International Journal of Dermatology. 2021;60(12):1449-1461. PubMed 33742704
• Product pages read in September 2026: Bulk Nutrients NMN Capsules, Herbs of Gold Resveratrol AdvantAGE, AgeMate Daily Longevity Blend, Vida Glow Natural Marine Collagen, and the Melrose FutureLab NMN 500mg and JSHealth NMN 500 + Resveratrol labels at Chemist Warehouse.
• Eternal Elixir product pages and labels: NMN 500mg, Trans-Resveratrol, Spermidine 10mg, Ca-AKG 500mg.